Susan L. Neuhausen
Epidemiology, School of Medicine
Pediatrics, School of Medicine
Phone: (949) 824-5769
Email: sneuhaus@uci.edu
http://www.faculty.uci.edu/profile.cfm?faculty_id=5149
http://www.faculty/profile.cfm?faculty_id=5149&name=Susan%20L.%20Neuhausen
Dept. of Epidemiology - School of Medicine
Susan Neuhausen
Dr. Neuhausen’s research is focused on identifying genes that cause and/or increase susceptibility to disease. Thus, she is actively involved in numerous research projects devoted to the study of several diseases, with her primary focus on breast cancer. Other cancers include prostate and colorectal cancers. The current projects are focused on identifying genetic variants in the insulin-like growth factor signaling pathway and environmental (lifestyle/diet) factors that affect risk of developing cancer, as well as cancer aggressiveness.
Selected Publications:
Nanda, R., Schumm, L. P., Cummings, S., Fackenthal, J. D., Sveen, L., Ademuyiwa, F., Cobleigh, M., Esserman, L., Lindor, N. M., Neuhausen, S. L., and Olopade, O. I. (2005). Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry. Jama 294(15), 1925-33.
Domchek, S. M., Friebel, T. M., Neuhausen, S. L., Wagner, T., Evans, G., Isaacs, C., Garber, J. E., Daly, M. B., Eeles, R., Matloff, E., Tomlinson, G. E., Van't Veer, L., Lynch, H. T., Olopade, O. I., Weber, B. L., and Rebbeck, T. R. (2006). Mortality after bilateral salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers: a prospective cohort study. Lancet Oncol 7(3), 223-9.
Antoniou, A. C., Sinilnikova, O. M., Simard, J., Leone, M., Dumont, M., Neuhausen, S. L., Struewing, J. P., Stoppa-Lyonnet, D., Barjhoux, L., Hughes, D. J., Coupier, I., Belotti, M., Lasset, C., Bonadona, V., Bignon, Y. J., Rebbeck, T. R., Wagner, T., Lynch, H. T., Domchek, S. M., Nathanson, K. L., Garber, J. E., Weitzel, J., Narod, S. A., Tomlinson, G., Olopade, O. I., Godwin, A., Isaacs, C., Jakubowska, A., Lubinski, J., Gronwald, J., Gorski, B., Byrski, T., Huzarski, T., Peock, S., Cook, M., Baynes, C., Murray, A., Rogers, M., Daly, P. A., Dorkins, H., Schmutzler, R. K., Versmold, B., Engel, C., Meindl, A., Arnold, N., Niederacher, D., Deissler, H., Spurdle, A. B., Chen, X., Waddell, N., Cloonan, N., Kirchhoff, T., Offit, K., Friedman, E., Kaufmann, B., Laitman, Y., Galore, G., Rennert, G., Lejbkowicz, F., Raskin, L., Andrulis, I. L., Ilyushik, E., Ozcelik, H., Devilee, P., Vreeswijk, M. P., Greene, M. H., Prindiville, S. A., Osorio, A., Benitez, J., Zikan, M., Szabo, C. I., Kilpivaara, O., Nevanlinna, H., Hamann, U., Durocher, F., Arason, A., Couch, F. J., Easton, D. F., and Chenevix-Trench, G. (2007). RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. Am J Hum Genet 81(6), 1186-200.
Garner, C. P., Ding, Y. C., John, E. M., Ingles, S. A., Olopade, O. I., Huo, D., Adebamowo, C., Ogundiran, T., and Neuhausen, S. L. (2008). Genetic variation in IGFBP2 and IGFBP5 is associated with breast cancer in populations of African descent. Hum Genet 123(3), 247-55.
Setiawan, V. W., Chu, L. H., John, E. M., Ding, Y. C., Ingles, S. A., Bernstein, L., Press, M. F., Ursin, G., Haiman, C. A., and Neuhausen, S. L. (2008). Mitochondrial DNA G10398A variant is not associated with breast cancer in African-American women. Cancer Genet Cytogenet 181(1), 16-9. |
