Dan Mercola
Pathology & Laboratory Medicine, School of Medicine
Phone: (949) 824-1298
Email: dmercola@uci.edu
http://www.ucihs.uci.edu/som/pathology/faculty/dmercola.html
Dan Mercola
Dr. Mercola is employing gene expression array-based methods to develop gene profiles for prognosis and treatment in prostate cancer in cooperation with an NIH consortium and participating biotechnology enterprises.
Selected Publications:
Virolle, T., Adamson, E. D., Baron, V., Birle, D., Mercola, D., Mustelin, T., and de Belle, I. (2001). The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling. Nat Cell Biol 3(12), 1124-8.
Krones-Herzig, A., Adamson, E., and Mercola, D. (2003). Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence. Proceedings of the National Academy of Sciences of the United States of America 100(6), 3233-3238.
Hayakawa, J., Mittal, S., Wang, Y., Korkmaz, K. S., Adamson, E., English, C., Ohmichi, M., McClelland, M., and Mercola, D. (2004). Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress. Mol Cell 16(4), 521-35.
Stuart, R. O., Wachsman, W., Berry, C. C., Wang-Rodriguez, J., Wasserman, L., Klacansky, I., Masys, D., Arden, K., Goodison, S., McClelland, M., Wang, Y., Sawyers, A., Kalcheva, I., Tarin, D., and Mercola, D. (2004). In silico dissection of cell-type-associated patterns of gene expression in prostate cancer. Proc Natl Acad Sci U S A 101(2), 615-20.
Yu, J., Baron, V., Mercola, D., Mustelin, T., and Adamson, E. D. (2007). A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells. Cell Death Differ 14(3), 436-46. |
