Hans-Ulrich Bernard
Molecular Biology & Biochemistry
School of Biological Sciences
Phone: (949) 824-5162
Email: hbernard@uci.edu
http://www.faculty.uci.edu/profile.cfm?faculty_id=4908
http://www.faculty.uci.edu/scripts/UCIFacultyProfiles/detailMBB.cfm?ID=4908
Hans Ulrich Bernard
Dr. Bernard is studying three topics:
1) Regulation of gene expression of papillomaviruses and its relevance for progression of cancer of the cervix.
2) Phylogenetic and genomic variability of papillomavirus genomes and its impact on the etiology and epidemiology of cancer of the cervix.
3) Cholinergic signaling during cervical carcinogenesis.
Selected Publications:
Kalantari, M., Calleja-Macias, I. E., Tewari, D., Hagmar, B., Lie, K., Barrera-Saldana, H. A., Wiley, D. J., and Bernard, H. U. (2004). Conserved methylation patterns of human papillomavirus type 16 DNA in asymptomatic infection and cervical neoplasia. J Virol 78(23), 12762-72.
Turan, T., Kalantari, M., Calleja-Macias, I. E., Cubie, H. A., Cuschieri, K., Villa, L. L., Skomedal, H., Barrera-Saldana, H. A., and Bernard, H. U. (2006). Methylation of the human papillomavirus-18 L1 gene: a biomarker of neoplastic progression? Virology 349(1), 175-83.
Balderas-Loaeza, A., Anaya-Saavedra, G., Ramirez-Amador, V. A., Guido-Jimenez, M. C., Kalantari, M., Calleja-Macias, I. E., Bernard, H. U., and Garcia-Carranca, A. (2007). Human papillomavirus-16 DNA methylation patterns support a causal association of the virus with oral squamous cell carcinomas. Int J Cancer 120(10), 2165-9.
Turan, T., Kalantari, M., Cuschieri, K., Cubie, H. A., Skomedal, H., and Bernard, H. U. (2007). High-throughput detection of human papillomavirus-18 L1 gene methylation, a candidate biomarker for the progression of cervical neoplasia. Virology 361(1), 185-93.
Kalantari, M., Lee, D., Calleja-Macias, I. E., Lambert, P. F., and Bernard, H. U. (2008). Effects of cellular differentiation, chromosomal integration and 5-aza-2'-deoxycytidine treatment on human papillomavirus-16 DNA methylation in cultured cell lines. Virology. |
